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Pulmonary embolism (PE) is the leading trigger of in-hospital death and the third most frequent cause of cardiovascular demise. The clinical presentation of PE is variable, and choosing the suitable remedy for particular person patients may be challenging. Traditionally, remedy of PE has concerned a selection of anticoagulation, thrombolysis or surgical procedure; nevertheless, a range of percutaneous interventional technologies have been developed which might be below investigation in patients with intermediate-high-danger or excessive-danger PE. These interventional applied sciences embrace catheter-directed thrombolysis (with or without ultrasound help), aspiration thrombectomy and mixtures of the aforementioned principles. These interventional treatment choices would possibly result in a extra fast enchancment in right ventricular perform and pulmonary and/or systemic haemodynamics specifically patients.